Zoryl MS IR 2/1000 mg Tablet - Strip of 10

Prescription Required

Compositions : Glimepiride 2mg + Metformin 1000mg + Sitagliptin 50mg

₹139.48 (Incl. GST)

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Manufacture/Marketer: Intas Pharmaceuticals Ltd.

Zoryl MS IR 2/1000 mg Tablet is a prescription medicine used to help control high blood sugar levels in adults with Type 2 Diabetes Mellitus. It contains three active ingredients: Glimepiride 2 mg, Metformin 1000 mg, and Sitagliptin 50 mg. Glimepiride is a sulfonylurea that stimulates the pancreas to release insulin. Metformin is a biguanide that reduces glucose production by the liver and improves the body's sensitivity to insulin. Sitagliptin is a DPP-4 inhibitor that helps increase insulin release when blood glucose levels are elevated and reduces the release of glucagon. This combination may be prescribed when blood sugar is not adequately controlled with diet, exercise, or other diabetes medicines. Zoryl MS IR 2/1000 mg Tablet should be used exactly as prescribed and as part of an overall diabetes-management plan.

Uses & Benefits

  • Helps control high blood sugar levels in adults with Type 2 Diabetes Mellitus.
  • Combines three medicines with different mechanisms of action to improve blood glucose control.
  • Glimepiride stimulates the pancreas to release insulin and helps lower blood sugar.
  • Metformin reduces glucose production by the liver and improves insulin sensitivity.
  • Sitagliptin helps increase glucose-dependent insulin release and reduce excess glucagon secretion.
  • May help improve both fasting and post-meal blood glucose levels when used as prescribed.
  • May be prescribed when blood sugar is not adequately controlled with simpler treatment regimens.
  • Consistent blood sugar control can help reduce the long-term risk of diabetes-related complications.
  • Works best when combined with a suitable diet, regular physical activity, and appropriate blood glucose monitoring.
How Zoryl MS IR 2/1000 mg Tablet works

  • Zoryl MS IR 2/1000 mg Tablet works through the combined actions of Glimepiride, Metformin, and Sitagliptin.
  • Glimepiride stimulates pancreatic beta cells to release insulin, helping glucose move from the blood into the body's cells.
  • Metformin reduces the amount of glucose produced by the liver and improves the body's response to insulin.
  • Sitagliptin inhibits the DPP-4 enzyme, increasing the activity of incretin hormones that promote insulin release when blood glucose is elevated.
  • Sitagliptin also reduces glucagon secretion, which helps prevent excessive glucose production by the liver.
  • The combined action of these three ingredients helps lower blood glucose through complementary mechanisms.
How to use Zoryl MS IR 2/1000 mg Tablet

  • Take Zoryl MS IR 2/1000 mg Tablet exactly as directed by your doctor.
  • It is generally taken with food to reduce the possibility of stomach-related side effects, but follow your doctor's specific instructions.
  • Swallow the tablet whole with a glass of water.
  • Do not crush, chew, or break the tablet unless your doctor or pharmacist specifically advises you to do so.
  • Try to take Zoryl MS IR 2/1000 mg Tablet at the same time each day if regular treatment has been prescribed.
  • Do not skip meals while taking a medicine containing Glimepiride, as missing meals can increase the risk of low blood sugar.
  • The appropriate dose depends on your blood glucose levels, kidney function, medical history, and response to treatment.
  • If you miss a dose, take it when you remember unless it is nearly time for your next dose. Do not take two doses together to make up for a missed dose.
  • Do not stop taking Zoryl MS IR 2/1000 mg Tablet on your own, even if your blood sugar improves. Consult your doctor before changing or stopping treatment.
Lifestyle Advice

  • Follow a balanced diet recommended for diabetes and limit foods and beverages containing excessive added sugar.
  • Exercise regularly according to your doctor's advice to improve insulin sensitivity and support overall health.
  • Monitor your blood glucose as recommended by your healthcare professional.
  • Avoid skipping meals, particularly while taking Glimepiride, because this can increase the risk of hypoglycemia.
  • Limit excessive alcohol consumption because alcohol can affect blood glucose levels and may increase certain medication-related risks.
  • Drink adequate fluids unless your doctor has advised you to restrict fluid intake.
  • Maintain a healthy body weight and attend regular diabetes check-ups.
  • Learn to recognize symptoms of low blood sugar, such as sweating, shaking, hunger, dizziness, weakness, confusion, or a fast heartbeat.

Side Effects

  • Common side effects may include nausea, vomiting, diarrhea, stomach discomfort, headache, dizziness, or weakness.
  • Metformin may cause gastrointestinal symptoms, particularly when treatment is started or the dose is increased.
  • Glimepiride may cause low blood sugar, especially if meals are skipped or food intake is inadequate.
  • Some patients may experience changes in blood glucose levels or other digestive symptoms while adjusting to the combination treatment.
  • Rare but serious symptoms should receive prompt medical attention, particularly severe or persistent hypoglycemia or symptoms suggesting a serious metabolic reaction.
  • If you experience persistent or troublesome side effects while taking Zoryl MS IR 2/1000 mg Tablet, contact your healthcare provider.

Precautions and Warnings

  • Do not use Zoryl MS IR 2/1000 mg Tablet if you have a known allergy to Glimepiride, Metformin, Sitagliptin, or any other ingredient in the formulation.
  • Patients with kidney disease should use this medicine only under appropriate medical supervision because Metformin requires particular caution in significant kidney impairment.
  • Inform your doctor about any liver disease, heart problems, or previous episodes of severe low blood sugar before starting treatment.
  • Avoid skipping meals while taking Glimepiride because inadequate food intake can increase the risk of hypoglycemia.
  • Pregnant or breastfeeding women should consult their healthcare provider before using Zoryl MS IR 2/1000 mg Tablet.
  • Avoid excessive alcohol consumption because it can affect blood glucose control and may increase medication-related risks.
  • Tell your doctor about all prescription medicines, over-the-counter medicines, supplements, and herbal products you are taking because some medicines may affect blood glucose or interact with the components of this combination.
  • Regular monitoring of blood glucose and kidney function may be recommended during treatment.
1. What is Zoryl MS IR 2/1000 mg Tablet used for?
Zoryl MS IR 2/1000 mg Tablet is used to help control high blood sugar levels in adults with Type 2 Diabetes Mellitus, particularly when simpler treatment approaches do not provide adequate control.

2. What are the ingredients in Zoryl MS IR 2/1000 mg Tablet?
Zoryl MS IR 2/1000 mg Tablet contains Glimepiride 2 mg, Metformin 1000 mg, and Sitagliptin 50 mg.

3. Can Zoryl MS IR 2/1000 mg Tablet cause low blood sugar?
Yes. Glimepiride can cause hypoglycemia, particularly when meals are skipped, food intake is inadequate, or it is combined with other glucose-lowering medicines. Symptoms may include sweating, shaking, hunger, dizziness, weakness, confusion, or a fast heartbeat.

4. What should I do if I forget to take a dose?
Take the missed dose when you remember unless it is close to the next scheduled dose. Do not take two doses at the same time to compensate for a missed dose.

5. Can I stop taking Zoryl MS IR 2/1000 mg Tablet if my blood sugar becomes normal?
No. Normal blood sugar may indicate that your diabetes treatment is working. Do not stop or change Zoryl MS IR 2/1000 mg Tablet without discussing it with your doctor.

6. Can I take Zoryl MS IR 2/1000 mg Tablet without changing my diet?
The medicine works best as part of a comprehensive diabetes-management plan. A balanced diet, regular physical activity, appropriate weight management, and blood glucose monitoring remain important.

7. Is Zoryl MS IR 2/1000 mg Tablet safe for long-term use?
It may be prescribed for long-term management of Type 2 Diabetes Mellitus when appropriate. Regular medical follow-up is important, particularly for monitoring blood glucose and kidney function.

5. What should I do if I develop symptoms of low blood sugar?
If you experience symptoms such as sweating, shaking, hunger, dizziness, weakness, confusion, or a fast heartbeat, check your blood glucose if possible and follow the hypoglycemia instructions provided by your healthcare professional. Severe or persistent symptoms require prompt medical attention.

6. Can Zoryl MS IR 2/1000 mg Tablet affect the kidneys?
Kidney function is important when using medicines containing Metformin and Sitagliptin. People with kidney problems may require dose adjustments or alternative treatment, so inform your doctor about any history of kidney disease.

Directions for Use

Use only as prescribed by your physician.

Storage and Disposal

Please refer to the product label for storage information.
SKU 158147
Country of Manufacture India
Manufacturer Address Intas Pharmaceuticals Ltd.
Return/Buy Back policy Non-returnable
Prescription Required Yes
Storage Please refer to the product label for storage information.
Seller Kogland Commerce Pvt Ltd (TN)

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