Simbrinza Ophthalmic Suspension - 5 ml

Prescription Required

Compositions : Brinzolamide 10mg + Brimonidine 2mg

₹600.12 (Incl. GST)

MRP :

In stock

Delivery within 2 to 7 Working Days

Manufacture/Marketer: J.B. Chemicals & Pharmaceuticals Ltd.

Simbrinza Ophthalmic Suspension is a prescription eye drop solution designed to manage elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. This innovative formulation combines two active ingredients: brimonidine tartrate and dorzolamide hydrochloride. Brimonidine tartrate is an alpha-2 adrenergic agonist that reduces the production of aqueous humor while increasing its outflow, effectively lowering IOP. Dorzolamide hydrochloride, on the other hand, is a carbonic anhydrase inhibitor that decreases the formation of bicarbonate ions, leading to reduced aqueous humor secretion. Together, these components work synergistically to provide a comprehensive approach to managing conditions associated with increased eye pressure. Simbrinza Ophthalmic Suspension is particularly beneficial for patients who may require multiple medications to achieve optimal IOP control, as it simplifies their treatment regimen by combining two effective agents into a single formulation. The suspension is typically administered in the affected eye(s) and is suitable for adults and children aged two years and older. With its dual-action mechanism, Simbrinza Ophthalmic Suspension not only helps in managing IOP but also enhances patient compliance by reducing the number of daily doses required. This product is an essential part of the therapeutic arsenal for ophthalmologists and healthcare providers aiming to preserve vision and prevent complications associated with glaucoma and ocular hypertension.

Uses & Benefits

  • Effectively lowers intraocular pressure in patients with open-angle glaucoma.
  • Reduces aqueous humor production and increases its outflow.
  • Combines two active ingredients for enhanced efficacy.
  • Helps prevent vision loss associated with elevated IOP.
  • Suitable for both adults and pediatric patients aged two years and older.
  • Improves patient adherence by minimizing the number of medications needed.
  • Can be used as an adjunct therapy with other IOP-lowering medications.
How Simbrinza Ophthalmic Suspension works

  • Brimonidine tartrate stimulates alpha-2 adrenergic receptors, leading to decreased aqueous humor production.
  • Dorzolamide hydrochloride inhibits carbonic anhydrase, reducing bicarbonate ion formation and subsequently lowering aqueous humor secretion.
  • The combination of these actions results in a significant reduction in intraocular pressure.
  • Simbrinza Ophthalmic Suspension provides a dual mechanism of action, enhancing overall therapeutic effectiveness.
How to use Simbrinza Ophthalmic Suspension

  • Administer one drop of Simbrinza Ophthalmic Suspension in the affected eye(s) twice daily.
  • Ensure to shake the bottle well before each use to maintain proper suspension consistency.
  • Do not touch the dropper tip to any surface to avoid contamination.
  • If using other eye medications, wait at least 10 minutes between applications.
  • Continue using as prescribed by your healthcare provider for optimal results.
  • If a dose is missed, administer it as soon as remembered unless it is close to the time for the next dose; do not double up on doses.
Lifestyle Advice

  • Maintain regular follow-up appointments with your eye care specialist to monitor intraocular pressure.
  • Adopt a healthy diet rich in antioxidants, such as leafy greens and fruits, which may support eye health.
  • Stay hydrated to promote overall health, including ocular health.
  • Avoid smoking and limit alcohol consumption, as these can negatively impact eye health.
  • Engage in regular physical activity to improve circulation and overall well-being.

Side Effects

  • Common side effects may include eye discomfort, burning or stinging upon application, and dry mouth.
  • Serious side effects can include allergic reactions such as rash, itching, or swelling of the face or throat; seek immediate medical attention if these occur.
  • If you experience sudden vision changes or severe eye pain, contact your healthcare provider promptly.

Precautions and Warnings

  • Avoid using Simbrinza Ophthalmic Suspension if you are allergic to any of its ingredients.
  • Use caution if you have a history of cardiovascular disease or depression.
  • Consult your doctor if you are breastfeeding, as brimonidine may pass into breast milk.
  • Alcohol consumption should be limited while using this medication due to potential interactions.
  • Monitor kidney and liver function regularly if you have pre-existing conditions affecting these organs.

1. What should I do if I accidentally miss a dose of Simbrinza Ophthalmic Suspension?
If you miss a dose, apply it as soon as you remember unless it's almost time for your next scheduled dose. In that case, skip the missed dose and continue with your regular dosing schedule.

2. Can I use Simbrinza Ophthalmic Suspension while pregnant?
Consult your healthcare provider before using Simbrinza Ophthalmic Suspension if you are pregnant or planning to become pregnant.

3. Are there any known drug interactions with Simbrinza Ophthalmic Suspension?
Yes, inform your doctor about all medications you are taking, including over-the-counter drugs and supplements, to avoid potential interactions.

4. How should I store Simbrinza Ophthalmic Suspension?
Store the suspension at room temperature away from light and moisture. Do not freeze.

5. Is it safe to drive after using Simbrinza Ophthalmic Suspension?
Some patients may experience temporary blurred vision after application. Wait until your vision clears before driving or operating machinery.

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SKU 177516
Country of Manufacture India
Manufacturer Address J.B. Chemicals & Pharmaceuticals Ltd.
Return/Buy Back policy Non-returnable
Prescription Required Yes
Seller Kogland Commerce Pvt Ltd (TN)

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