Pregabid D 50/10 mg Capsule - Strip of 10

Prescription Required

Compositions : Pregabalin 50mg + Duloxetine 10mg

₹119.54 (Incl. GST)

MRP :

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Delivery within 2 to 7 Working Days

Manufacture/Marketer: Intas Pharmaceuticals Ltd.

Pregabid is a unique pharmaceutical formulation designed to address chronic neuropathic pain and anxiety-related discomfort through its synergistic combination of two active ingredients: Duloxetine and Pregabalin. Pregabid is classified as a dual-action medication that effectively targets both the physical and emotional aspects of pain. The key composition of Pregabid includes 50 mg of Duloxetine, a serotonin-norepinephrine reuptake inhibitor (SNRI), and 20 mg of Pregabalin, a member of the gabapentinoid class. This combination allows Pregabid to modulate pain signals in the central nervous system while also enhancing mood regulation. The primary purpose of Pregabid is to provide relief from conditions such as diabetic peripheral neuropathic pain, fibromyalgia, and generalized anxiety disorder. By addressing both the sensory and affective components of chronic pain, Pregabid offers a comprehensive therapeutic approach that can significantly improve patients' quality of life. The therapeutic category of Pregabid encompasses pain management and mental health support, making it a versatile option for individuals suffering from complex pain syndromes. With its innovative formulation, Pregabid not only alleviates pain but also helps in managing the emotional distress that often accompanies chronic conditions. This dual mechanism of action is what sets Pregabid apart from traditional analgesics, which typically focus solely on physical symptoms. As a result, Pregabid represents a significant advancement in the treatment of chronic pain and anxiety, providing patients with a holistic solution that addresses multiple facets of their health.

Uses & Benefits

  • Pregabid provides multidimensional pain relief by targeting both central and peripheral pain mechanisms.
  • This formulation is effective for treating diabetic peripheral neuropathic pain.
  • Pregabid helps alleviate fibromyalgia symptoms, improving overall comfort.
  • Patients using Pregabid often experience enhanced emotional well-being due to Duloxetine's action on serotonin levels.
  • By reducing the need for opioids, Pregabid minimizes the risks associated with opioid use.
  • Pregabid simplifies treatment regimens with its fixed-dose combination, promoting better adherence.
  • Improved functional outcomes are reported by patients taking Pregabid, including better mobility and sleep quality.
  • This therapy can help manage anxiety components associated with chronic pain syndromes.
How Pregabid works

Pregabid-D 50/20 Capsule DR combines two powerful medications: Pregabalin and Duloxetine. Together, they work synergistically to relieve neuropathic pain by modulating nerve activity and neurotransmitter levels.


  • Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels, reducing excitatory neurotransmitter release.
  • Duloxetine increases serotonin and norepinephrine levels in the brain, which helps inhibit pain signal transmission.
  • This combination addresses both the physical sensations of pain and the emotional distress associated with chronic conditions.
  • Pregabid effectively reduces abnormal neuronal firing linked to neuropathic pain.
  • The dual mechanism allows for a more comprehensive approach to pain management than either drug alone.
  • Pregabid's formulation ensures effective concentrations in the central nervous system for optimal therapeutic effects.
How to use Pregabid

  • Pregabid should be taken exactly as prescribed by a healthcare professional.
  • The recommended dosage is typically once daily, preferably at the same time each day.
  • This medication can be taken with or without food; however, taking it with food may help reduce stomach upset.
  • Swallow the capsule whole with a glass of water; do not crush or chew it.
  • Maintaining consistent timing is crucial for preserving stable blood drug levels.
  • Do not abruptly stop taking Pregabid without consulting your doctor, as this may worsen symptoms or lead to withdrawal effects.
  • Consult your healthcare provider for any adjustments in dosage based on individual response and tolerability.
Lifestyle Advice

  • Maintain hydration by drinking plenty of fluids to help mitigate side effects associated with Pregabid.
  • A balanced diet rich in nutrients can support overall health while using this medication.
  • Monitor mood and behavior closely; report any significant changes to your healthcare provider promptly.
  • Avoid abrupt cessation of Pregabid; consult your doctor for any changes in treatment plans.
  • Practice sun protection measures if experiencing photosensitivity while on Pregabid.
  • Regularly check blood pressure during the initial treatment phase to ensure stability.

Side Effects

  • Common side effects of Pregabid include nausea, dizziness, fatigue, and dry mouth.
  • Some patients may experience sleep disturbances or gastrointestinal issues like constipation or diarrhea.
  • Less common side effects can include blurred vision, weight changes, and mood alterations.
  • Serious side effects requiring immediate medical attention include severe allergic reactions and suicidal thoughts.
  • Patients should monitor for unusual changes in mood or behavior while on Pregabid.
  • Older adults may be at higher risk for serious adverse reactions; close monitoring is advised.

Precautions and Warnings

  • Pregabid should not be used in patients with a known hypersensitivity to Duloxetine or Pregabalin.
  • Caution is advised for individuals with liver or kidney impairment; dose adjustments may be necessary.
  • Alcohol consumption should be avoided as it can exacerbate side effects like dizziness and sedation.
  • Pregnancy and breastfeeding require careful consideration; consult a healthcare provider before use.
  • Patients should be monitored for mood changes, especially those with a history of depression or suicidal ideation.
  • Driving or operating heavy machinery should be avoided until individual tolerance to Pregabid is established.
1. What conditions does Pregabid treat?
Pregabid is effective for managing chronic nerve pain, fibromyalgia, diabetic neuropathy, and anxiety-related discomfort.
2. How quickly does Pregabid start working?
Some patients may notice pain relief within 1-2 weeks, while optimal effects are typically observed after 4-6 weeks.
3. Is alcohol safe to consume while taking Pregabid?
No, alcohol should be avoided as it can increase the risk of side effects such as dizziness and sedation.
4. Can Pregabid be used long-term?
Yes, under medical supervision, Pregabid may be used long-term if necessary.
5. Does Pregabid affect mood?
Yes, Duloxetine can influence mood; any changes should be reported to a healthcare provider.
6. Is Pregabid safe for elderly patients?
With appropriate dose adjustments and monitoring, Pregabid can be safely used in elderly patients.
7. What should I do if I miss a dose of Pregabid?
Take the missed dose as soon as you remember unless it's close to the next scheduled dose.

Directions for Use

Use only as prescribed by your physician.

Storage and Disposal

Please refer to the product label for storage information.
SKU 145159
Country of Manufacture India
Manufacturer Address Intas Pharmaceuticals Ltd.
Return/Buy Back policy Non-returnable
Prescription Required Yes
Storage Please refer to the product label for storage information.
Seller Kogland Commerce Pvt Ltd (TN)

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