Kombiglyze XR 5/1000 mg Tablet is a prescription medication primarily used in the management of type 2 diabetes mellitus. This pharmaceutical product combines two active ingredients: saxagliptin and metformin hydrochloride. Saxagliptin is a DPP-4 inhibitor that helps to increase insulin secretion and decrease glucagon levels in the bloodstream, thereby improving glycemic control. Metformin, on the other hand, is a biguanide that works by decreasing hepatic glucose production and enhancing insulin sensitivity in peripheral tissues. The combination of these two agents in Kombiglyze XR 5/1000 mg Tablet provides a synergistic effect, making it an effective option for patients who require more than one medication to achieve optimal blood sugar levels. The extended-release formulation allows for once-daily dosing, which can improve adherence to the treatment regimen. This medication is typically prescribed for adults with type 2 diabetes who are not adequately controlled on metformin alone or for those who may benefit from the addition of saxagliptin to their treatment plan. It is important for patients to use Kombiglyze XR 5/1000 mg Tablet as part of a comprehensive diabetes management program that includes diet, exercise, and regular monitoring of blood glucose levels. As with any medication, it is essential to follow the healthcare provider's instructions regarding its use and to discuss any concerns or questions with them.
Uses & Benefits
Helps control blood sugar levels in adults with type 2 diabetes.
Combines the effects of saxagliptin and metformin for enhanced glycemic control.
Reduces the risk of diabetes-related complications.
Improves insulin sensitivity and decreases hepatic glucose production.
Convenient once-daily dosing due to extended-release formulation.
Can be used in conjunction with diet and exercise for better management of diabetes.
May be prescribed when metformin alone does not provide adequate control.
How Kombiglyze XR 5/1000 mg Tablet works
Saxagliptin inhibits the DPP-4 enzyme, leading to increased levels of incretin hormones.
Increased incretin levels enhance insulin secretion from pancreatic beta cells in response to meals.
Metformin reduces glucose production in the liver and improves insulin sensitivity in muscle and fat tissues.
The combination of saxagliptin and metformin results in improved overall glycemic control.
How to use Kombiglyze XR 5/1000 mg Tablet
Take Kombiglyze XR 5/1000 mg Tablet orally, with food to reduce gastrointestinal side effects.
The usual starting dose is one tablet taken once daily.
Dosage may be adjusted based on individual blood glucose levels and tolerance.
Do not crush or chew the tablet; swallow it whole with a glass of water.
Maintain regular monitoring of blood glucose levels as advised by your healthcare provider.
If a dose is missed, take it as soon as you remember unless it is close to the time for your next dose.
Do not double up on doses to make up for a missed one.
Lifestyle Advice
Adopt a balanced diet rich in whole grains, fruits, vegetables, and lean proteins.
Engage in regular physical activity, aiming for at least 150 minutes of moderate exercise per week.
Monitor blood sugar levels regularly to understand how food and activity affect your diabetes management.
Avoid excessive consumption of sugary foods and beverages that can spike blood glucose levels.
Stay hydrated by drinking plenty of water throughout the day.
Maintain a healthy weight through diet and exercise to improve insulin sensitivity.
Side Effects
Common side effects include nausea, vomiting, diarrhea, abdominal pain, and headache.
Serious side effects may include lactic acidosis, pancreatitis, and severe allergic reactions.
If you experience symptoms such as unusual tiredness, muscle pain, or difficulty breathing, seek medical attention immediately.
Monitor for signs of low blood sugar (hypoglycemia), such as dizziness, sweating, or confusion.
Precautions and Warnings
Avoid use if you have a known allergy to saxagliptin, metformin, or any other components of Kombiglyze XR 5/1000 mg Tablet.
Use caution if you have kidney or liver problems; dosage adjustments may be necessary.
Consult your healthcare provider before using this medication if you are pregnant or breastfeeding.
Avoid alcohol consumption while taking this medication as it can increase the risk of lactic acidosis.
Be cautious when driving or operating machinery until you know how Kombiglyze XR 5/1000 mg Tablet affects you.
1. What should I do if I miss a dose of Kombiglyze XR 5/1000 mg Tablet? If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not take two doses at once.
2. Can I take Kombiglyze XR 5/1000 mg Tablet if I am pregnant? Consult your healthcare provider before using Kombiglyze XR 5/1000 mg Tablet during pregnancy, as it may not be safe.
3. Are there any food interactions with Kombiglyze XR 5/1000 mg Tablet? It is advisable to take Kombiglyze XR 5/1000 mg Tablet with food to minimize gastrointestinal side effects.
4. What are the common side effects of Kombiglyze XR 5/1000 mg Tablet? Common side effects may include nausea, diarrhea, headache, and abdominal pain.
5. Who should avoid taking Kombiglyze XR 5/1000 mg Tablet? Individuals with severe kidney impairment or those with a history of hypersensitivity to its components should avoid this medication.
6. How should I store Kombiglyze XR 5/1000 mg Tablet? Store Kombiglyze XR 5/1000 mg Tablet at room temperature away from moisture and heat.
No content available for this section.
SKU
172931
Country of Manufacture
India
Manufacturer Address
AstraZeneca India
Return/Buy Back policy
Non-returnable
Prescription Required
Yes
Seller
Kogland Commerce Pvt Ltd (TN)
Kombiglyze XR 5/1000 mg Tablet is a prescription medication primarily used in the management of type 2 diabetes mellitus. This pharmaceutical product combines two active ingredients: saxagliptin and metformin hydrochloride. Saxagliptin is a DPP-4 inhibitor that helps to increase insulin secretion and decrease glucagon levels in the bloodstream, thereby improving glycemic control. Metformin, on the other hand, is a biguanide that works by decreasing hepatic glucose production and enhancing insulin sensitivity in peripheral tissues. The combination of these two agents in Kombiglyze XR 5/1000 mg Tablet provides a synergistic effect, making it an effective option for patients who require more than one medication to achieve optimal blood sugar levels. The extended-release formulation allows for once-daily dosing, which can improve adherence to the treatment regimen. This medication is typically prescribed for adults with type 2 diabetes who are not adequately controlled on metformin alone or for those who may benefit from the addition of saxagliptin to their treatment plan. It is important for patients to use Kombiglyze XR 5/1000 mg Tablet as part of a comprehensive diabetes management program that includes diet, exercise, and regular monitoring of blood glucose levels. As with any medication, it is essential to follow the healthcare provider's instructions regarding its use and to discuss any concerns or questions with them.
Uses & Benefits
Helps control blood sugar levels in adults with type 2 diabetes.
Combines the effects of saxagliptin and metformin for enhanced glycemic control.
Reduces the risk of diabetes-related complications.
Improves insulin sensitivity and decreases hepatic glucose production.
Convenient once-daily dosing due to extended-release formulation.
Can be used in conjunction with diet and exercise for better management of diabetes.
May be prescribed when metformin alone does not provide adequate control.
How Kombiglyze XR 5/1000 mg Tablet works
Saxagliptin inhibits the DPP-4 enzyme, leading to increased levels of incretin hormones.
Increased incretin levels enhance insulin secretion from pancreatic beta cells in response to meals.
Metformin reduces glucose production in the liver and improves insulin sensitivity in muscle and fat tissues.
The combination of saxagliptin and metformin results in improved overall glycemic control.
How to use Kombiglyze XR 5/1000 mg Tablet
Take Kombiglyze XR 5/1000 mg Tablet orally, with food to reduce gastrointestinal side effects.
The usual starting dose is one tablet taken once daily.
Dosage may be adjusted based on individual blood glucose levels and tolerance.
Do not crush or chew the tablet; swallow it whole with a glass of water.
Maintain regular monitoring of blood glucose levels as advised by your healthcare provider.
If a dose is missed, take it as soon as you remember unless it is close to the time for your next dose.
Do not double up on doses to make up for a missed one.
Lifestyle Advice
Adopt a balanced diet rich in whole grains, fruits, vegetables, and lean proteins.
Engage in regular physical activity, aiming for at least 150 minutes of moderate exercise per week.
Monitor blood sugar levels regularly to understand how food and activity affect your diabetes management.
Avoid excessive consumption of sugary foods and beverages that can spike blood glucose levels.
Stay hydrated by drinking plenty of water throughout the day.
Maintain a healthy weight through diet and exercise to improve insulin sensitivity.
Side Effects
Common side effects include nausea, vomiting, diarrhea, abdominal pain, and headache.
Serious side effects may include lactic acidosis, pancreatitis, and severe allergic reactions.
If you experience symptoms such as unusual tiredness, muscle pain, or difficulty breathing, seek medical attention immediately.
Monitor for signs of low blood sugar (hypoglycemia), such as dizziness, sweating, or confusion.
Precautions and Warnings
Avoid use if you have a known allergy to saxagliptin, metformin, or any other components of Kombiglyze XR 5/1000 mg Tablet.
Use caution if you have kidney or liver problems; dosage adjustments may be necessary.
Consult your healthcare provider before using this medication if you are pregnant or breastfeeding.
Avoid alcohol consumption while taking this medication as it can increase the risk of lactic acidosis.
Be cautious when driving or operating machinery until you know how Kombiglyze XR 5/1000 mg Tablet affects you.
1. What should I do if I miss a dose of Kombiglyze XR 5/1000 mg Tablet? If you miss a dose, take it as soon as you remember unless it's almost time for your next dose. Do not take two doses at once.
2. Can I take Kombiglyze XR 5/1000 mg Tablet if I am pregnant? Consult your healthcare provider before using Kombiglyze XR 5/1000 mg Tablet during pregnancy, as it may not be safe.
3. Are there any food interactions with Kombiglyze XR 5/1000 mg Tablet? It is advisable to take Kombiglyze XR 5/1000 mg Tablet with food to minimize gastrointestinal side effects.
4. What are the common side effects of Kombiglyze XR 5/1000 mg Tablet? Common side effects may include nausea, diarrhea, headache, and abdominal pain.
5. Who should avoid taking Kombiglyze XR 5/1000 mg Tablet? Individuals with severe kidney impairment or those with a history of hypersensitivity to its components should avoid this medication.
6. How should I store Kombiglyze XR 5/1000 mg Tablet? Store Kombiglyze XR 5/1000 mg Tablet at room temperature away from moisture and heat.
No content available for this section.
SKU
172931
Country of Manufacture
India
Manufacturer Address
AstraZeneca India
Return/Buy Back policy
Non-returnable
Prescription Required
Yes
Seller
Kogland Commerce Pvt Ltd (TN)
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