Istamet XR Tablet - Strip of 10

Prescription Required

Compositions : Sitagliptin 100mg + Metformin 1000mg

₹146.78 (Incl. GST)

MRP :

In stock

Delivery within 2 to 7 Working Days

Manufacture/Marketer: Sun Pharmaceutical Industries Ltd

Istamet XR Tablet is a prescription medication specifically designed to assist adults in managing blood sugar levels effectively, particularly for those diagnosed with type 2 diabetes mellitus. This innovative formulation combines two active ingredients: Metformin and Sitagliptin, which work synergistically to enhance glucose regulation in the body. Metformin, a member of the biguanide class, plays a crucial role in lowering blood sugar levels by reducing glucose production in the liver, improving insulin sensitivity, and slowing down the absorption of sugar from food within the intestines. On the other hand, Sitagliptin is classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor. It functions by increasing the levels of natural incretin hormones, which stimulate the pancreas to release more insulin after meals while simultaneously decreasing the amount of glucose produced by the liver. The combination of these two powerful agents in Istamet XR Tablet is particularly beneficial when lifestyle modifications such as diet and exercise, along with single-agent therapy, fail to achieve adequate blood sugar control. By utilizing both Metformin and Sitagliptin, Istamet XR Tablet helps maintain lower blood sugar levels throughout the day, especially after meals, thereby reducing the risk of long-term complications associated with type 2 diabetes, including cardiovascular disease, chronic kidney disease, and diabetic neuropathy. Regular monitoring of blood sugar levels and kidney function is recommended during treatment with Istamet XR Tablet to ensure optimal management of diabetes and to tailor the dosage according to individual patient needs. Your healthcare provider will determine the most appropriate dosage and formulation for your specific condition, ensuring that you receive the best possible care while using Istamet XR Tablet.

Uses & Benefits

  • Istamet XR Tablet provides dual-action glucose-lowering effects targeting both liver glucose output and pancreatic insulin response.
  • This medication significantly reduces HbA1c levels, aiding in achieving target glycaemic goals.
  • Lower risk of hypoglycaemia compared to other diabetes medications like sulfonylureas when using Istamet XR Tablet.
  • Weight-neutral profile minimizes the risk of weight gain associated with diabetes treatments.
  • Favorable safety record with good tolerability in most patients using Istamet XR Tablet.
  • Simplified treatment regimen through a single combination tablet available in both immediate-release and extended-release formulations.
  • Helps manage both fasting and postprandial blood glucose levels effectively.
  • Reduces the risk of long-term complications related to type 2 diabetes, such as cardiovascular issues and neuropathy.
How Istamet XR Tablet works

Istamet XR Tablet combines two effective medications: Sitagliptin and Metformin. This combination works synergistically to improve blood sugar control in individuals with type 2 diabetes. Sitagliptin enhances insulin secretion from the pancreas while reducing hepatic glucose production. Metformin decreases glucose production in the liver and increases insulin sensitivity.
How to use Istamet XR Tablet

  • Take Istamet XR Tablet exactly as prescribed by your healthcare provider.
  • Administer the tablet with meals to minimize gastrointestinal discomfort.
  • Typically taken once or twice daily based on your doctor's recommendations.
  • Swallow the extended-release tablets whole; do not crush or chew them.
  • Maintain a consistent schedule by taking your medication at the same time each day.
  • Regularly monitor your blood sugar levels as directed by your healthcare provider.
  • Do not discontinue use of Istamet XR Tablet without consulting your doctor first.
  • Your doctor will determine the appropriate dosage based on your individual needs and response to treatment.
Lifestyle Advice

  • Incorporate regular physical activity into your daily routine to enhance blood sugar control while using Istamet XR Tablet.
  • Maintain a balanced diet rich in whole grains, fruits, vegetables, and lean proteins to support overall health.
  • Avoid excessive consumption of high-fat meals that may exacerbate gastrointestinal side effects associated with Istamet XR Tablet.
  • Carry a source of fast-acting sugar for emergencies in case of hypoglycemia episodes while on Istamet XR Tablet.
  • Regularly check your feet for any sores or infections as part of diabetes management while using Istamet XR Tablet.
  • Ensure annual kidney function tests are conducted while on Istamet XR Tablet to monitor for any potential complications.

Side Effects

  • Common side effects of Istamet XR Tablet include stomach upset, nausea, and diarrhea.
  • Mild headaches and cold-like symptoms such as a runny nose or sore throat may occur.
  • Uncommon side effects may include skin rash, joint pain, changes in taste, or mild swelling of extremities.
  • Serious side effects requiring immediate medical attention include lactic acidosis, characterized by severe fatigue, muscle pain, or difficulty breathing.
  • Pancreatitis symptoms may include severe abdominal pain radiating to the back; seek medical help if these occur.
  • Monitor for rare elevations in liver enzymes that may necessitate medical evaluation.
  • Severe allergic reactions may manifest as swelling of the face or difficulty breathing; consult a doctor immediately if these symptoms arise.

Precautions and Warnings

  • Istamet XR Tablet should not be used in patients with known allergies to its components or those with severe kidney or liver impairment.
  • Avoid use in cases of congestive heart failure or lactic acidosis history.
  • Consult your doctor before using Istamet XR Tablet if pregnant or breastfeeding; risks versus benefits must be assessed.
  • Limit alcohol consumption while taking Istamet XR Tablet due to increased risk of lactic acidosis.
  • Regular kidney function monitoring is essential during treatment with Istamet XR Tablet.
  • Caution is advised when driving or operating machinery if experiencing low blood sugar symptoms.
  • Inform your healthcare provider about all medications you are taking to avoid potential interactions.
1. What is Istamet XR Tablet used for?
Istamet XR Tablet is utilized for improving blood sugar control in adults diagnosed with type 2 diabetes. It is prescribed when lifestyle changes and single medications are insufficient.
2. How does Istamet XR Tablet work?
The formulation aids in enhancing insulin effectiveness and reducing excess glucose production by the liver. This dual action improves overall blood sugar management.
3. When should I take Istamet XR Tablet?
It is generally recommended to take Istamet XR Tablet with meals to minimize gastrointestinal discomfort. Follow your doctor's specific instructions regarding timing.
4. How long does it take for Istamet XR Tablet to lower blood sugar?
Initial improvements may be observed within days; however, significant benefits typically manifest over several weeks with consistent use.
5. Can Istamet XR Tablet cause low blood sugar?
While it usually does not lead to low blood sugar on its own, combining it with insulin or certain other medications may increase this risk.
6. What are common side effects of Istamet XR Tablet?
Common side effects include nausea, diarrhea, and mild stomach discomfort. These effects often improve over time.
7. Is Istamet XR Tablet safe for long-term use?
Yes, it is frequently used long-term under medical supervision. Regular monitoring of blood sugar and kidney function is essential.

Directions for Use

Use only as prescribed by your physician.

Storage and Disposal

Please refer to the product label for storage information.
SKU 291063
Country of Manufacture India
Manufacturer Address Sun Pharmaceutical Industries Ltd
Return/Buy Back policy Non-returnable
Prescription Required Yes
Storage Please refer to the product label for storage information.
Seller Kogland Commerce Pvt Ltd (TN)

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