Istamet XR 500 Tablet - Strip of 10

Prescription Required

Compositions : Metformin Hydrochloride 500mg + Sitagliptin 100mg

₹110.70 (Incl. GST)

MRP :

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Delivery within 2 to 7 Working Days

Manufacture/Marketer: Sun Pharmaceutical Industries Ltd

Istamet XR 500 Tablet is a prescription medication primarily used in the management of type 2 diabetes mellitus. This extended-release formulation combines two active ingredients: Metformin and Sitagliptin. Metformin is a biguanide that helps to lower glucose production in the liver and improve insulin sensitivity, while Sitagliptin is a DPP-4 inhibitor that increases incretin levels, leading to enhanced insulin secretion in response to meals. Together, these components work synergistically to control blood sugar levels effectively. Istamet XR 500 Tablet is designed for once-daily dosing, providing a convenient option for patients who require glycemic control. The extended-release formulation allows for a gradual release of the medication into the bloodstream, minimizing the risk of gastrointestinal side effects commonly associated with immediate-release formulations. This makes Istamet XR 500 Tablet an ideal choice for patients seeking a stable and effective treatment regimen for their diabetes management. It is essential for patients to use this medication as part of a comprehensive diabetes care plan that includes diet, exercise, and regular monitoring of blood glucose levels. The therapeutic purpose of Istamet XR 500 Tablet is to help achieve and maintain optimal glycemic control, thereby reducing the risk of diabetes-related complications such as cardiovascular disease, neuropathy, and nephropathy. As with any medication, it is crucial for patients to consult with their healthcare provider to determine if Istamet XR 500 Tablet is suitable for their individual health needs and to discuss any potential interactions with other medications they may be taking.

Uses & Benefits

  • Helps in controlling blood sugar levels in adults with type 2 diabetes.
  • Reduces the risk of diabetes-related complications.
  • Improves insulin sensitivity and decreases hepatic glucose production.
  • Enhances incretin levels to stimulate insulin secretion post-meal.
  • Convenient once-daily dosing for better adherence.
  • Extended-release formulation minimizes gastrointestinal side effects.
  • Can be used in conjunction with diet and exercise for optimal results.
  • May be prescribed alone or in combination with other antidiabetic medications.
How Istamet XR 500 Tablet works

  • Metformin decreases glucose production in the liver and enhances insulin sensitivity in peripheral tissues.
  • Sitagliptin inhibits the DPP-4 enzyme, leading to increased levels of incretin hormones.
  • Increased incretin levels promote insulin secretion from pancreatic beta cells in response to meals.
  • Reduces glucagon secretion, which lowers hepatic glucose output.
  • Overall, this dual action helps to maintain stable blood glucose levels throughout the day.
How to use Istamet XR 500 Tablet

  • Take Istamet XR 500 Tablet orally with food to reduce gastrointestinal discomfort.
  • The usual starting dose is one tablet once daily, as directed by your healthcare provider.
  • Do not crush or chew the tablet; swallow it whole with a glass of water.
  • Timing should be consistent each day to maintain stable blood levels of the medication.
  • Dosage may be adjusted based on individual blood glucose response and tolerability.
  • Continue taking Istamet XR 500 Tablet even if you feel well; do not stop without consulting your doctor.
  • Regular monitoring of blood glucose levels is recommended to assess treatment effectiveness.
Lifestyle Advice

  • Maintain a balanced diet rich in whole grains, fruits, vegetables, and lean proteins.
  • Engage in regular physical activity, aiming for at least 150 minutes of moderate exercise weekly.
  • Monitor blood sugar levels regularly as advised by your healthcare provider.
  • Avoid excessive consumption of sugary foods and beverages that can spike blood glucose levels.
  • Stay hydrated by drinking plenty of water throughout the day.
  • Manage stress through relaxation techniques such as yoga or meditation.
  • Keep regular appointments with your healthcare team for ongoing diabetes management support.

Side Effects

  • Common side effects may include nausea, vomiting, diarrhea, abdominal pain, and loss of appetite.
  • Serious side effects can include lactic acidosis, which is a medical emergency requiring immediate attention.
  • Seek medical help if you experience symptoms such as unusual tiredness, muscle pain, difficulty breathing, or stomach pain accompanied by nausea or vomiting.
  • Allergic reactions may occur; watch for signs like rash, itching, or swelling of the face/tongue/throat.

Precautions and Warnings

  • Avoid use if you have a known hypersensitivity to Metformin or Sitagliptin.
  • Use caution if you have kidney or liver problems; dosage adjustments may be necessary.
  • Monitor blood sugar levels closely if you are also taking other antidiabetic medications.
  • Avoid alcohol consumption due to increased risk of lactic acidosis and hypoglycemia.
  • Consult your doctor before using during pregnancy or breastfeeding; benefits must outweigh risks.
  • Be cautious when driving or operating machinery until you know how Istamet XR 500 Tablet affects you.
1. Is Istamet XR 500 Tablet safe for everyone?
Istamet XR 500 Tablet may not be suitable for individuals with certain medical conditions such as severe kidney impairment or those who are allergic to its components. Always consult your healthcare provider before starting any new medication.

2. What should I do if I miss a dose of Istamet XR 500 Tablet?
If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.

3. Can I take Istamet XR 500 Tablet with other medications?
Yes, but it's important to inform your doctor about all medications you are currently taking to avoid potential interactions.

4. How should I store Istamet XR 500 Tablet?
Store Istamet XR 500 Tablet at room temperature away from moisture and heat. Keep it out of reach of children.

5. What are the common side effects of Istamet XR 500 Tablet?
Common side effects may include gastrointestinal issues such as nausea, diarrhea, or abdominal discomfort. If these persist or worsen, contact your healthcare provider.

6. Can I drink alcohol while taking Istamet XR 500 Tablet?
It's advisable to limit alcohol intake while on Istamet XR 500 Tablet as it can affect blood sugar levels and increase the risk of lactic acidosis.

7. Is it safe to use Istamet XR 500 Tablet during pregnancy?
Consult your healthcare provider if you are pregnant or planning to become pregnant, as they will evaluate the risks and benefits specific to your situation.

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SKU 291065
Country of Manufacture India
Manufacturer Address Sun Pharmaceutical Industries Ltd
Return/Buy Back policy Non-returnable
Prescription Required Yes
Seller Kogland Commerce Pvt Ltd (TN)

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