Istamet XR 500 mg Tablet - Strip of 15

Prescription Required

Compositions : Metformin 500mg + Sitagliptin 100mg

₹181.42 (Incl. GST)

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Delivery within 2 to 7 Working Days

Manufacture/Marketer: Sun Pharmaceutical Industries Ltd

Istamet XR 500 mg Tablet is a prescription medication designed to assist in managing blood sugar levels in adults diagnosed with type 2 diabetes mellitus. This innovative formulation combines two active ingredients, Metformin and Sitagliptin, which work synergistically to enhance glucose regulation in the body. The primary purpose of Istamet XR 500 mg Tablet is to provide effective glycemic control, particularly when lifestyle modifications such as diet and exercise, along with single-agent therapy, fail to achieve desired blood sugar levels. Metformin, a member of the biguanide class, plays a crucial role in lowering blood sugar by reducing hepatic glucose production, improving insulin sensitivity, and slowing down the absorption of sugar from food in the intestines. On the other hand, Sitagliptin is classified as a dipeptidyl peptidase-4 (DPP-4) inhibitor, which increases the levels of natural incretin hormones. These hormones stimulate the pancreas to release more insulin post-meals and decrease glucose production by the liver. The combination of these two powerful agents in Istamet XR 500 mg Tablet not only helps lower blood sugar levels throughout the day but also minimizes the risk of long-term complications associated with type 2 diabetes, such as cardiovascular diseases, chronic kidney disease, and diabetic neuropathy. Regular monitoring of blood sugar levels and kidney function is recommended during treatment with Istamet XR 500 mg Tablet to ensure optimal therapeutic outcomes and safety. Your healthcare provider will determine the most suitable dosage and formulation based on your individual health needs, making Istamet XR 500 mg Tablet a vital component in the management of type 2 diabetes.

Uses & Benefits

  • Istamet XR 500 mg Tablet provides dual-action glucose-lowering effects targeting both liver glucose output and pancreatic insulin response.
  • This formulation significantly reduces HbA1c levels, aiding in achieving target glycemic goals.
  • Lower risk of hypoglycemia compared to other diabetes medications like sulfonylureas is associated with Istamet XR 500 mg Tablet.
  • Weight-neutral profile minimizes the risk of weight gain while using Istamet XR 500 mg Tablet.
  • Favorable safety record with good tolerability in most patients taking Istamet XR 500 mg Tablet.
  • Simplified treatment regimen through a single combination tablet available in extended-release formulation.
  • Helps manage both fasting and postprandial blood glucose levels effectively.
  • Reduces the risk of long-term complications related to type 2 diabetes when using Istamet XR 500 mg Tablet.
How Istamet XR 500 mg Tablet works

Istamet XR 500 mg Tablet combines two effective medications: Metformin and Sitagliptin. Together, they work to improve blood sugar control through complementary mechanisms.
  • Metformin decreases glucose production in the liver and enhances insulin sensitivity.
  • Sitagliptin promotes increased insulin secretion from the pancreas after meals.
  • This combination effectively lowers blood sugar levels throughout the day.
  • By reducing hepatic glucose output and enhancing insulin response, Istamet XR 500 mg Tablet provides better overall glycemic control.
  • The formulation also helps delay glucose absorption from the intestines.
  • Regular use of Istamet XR 500 mg Tablet can lead to improved HbA1c levels over time.
How to use Istamet XR 500 mg Tablet

  • Take Istamet XR 500 mg Tablet exactly as prescribed by your healthcare provider.
  • Administer the tablet with meals to minimize gastrointestinal discomfort.
  • The typical dosage is once or twice daily, depending on your doctor's recommendations.
  • Swallow the extended-release tablet whole; do not crush or chew it.
  • Maintain a consistent schedule by taking Istamet XR 500 mg Tablet at the same time each day.
  • Regularly monitor your blood sugar levels as instructed by your healthcare professional.
  • Do not discontinue use of Istamet XR 500 mg Tablet without consulting your doctor first.
Lifestyle Advice

  • Incorporate regular physical activity into your daily routine to enhance blood sugar control while using Istamet XR 500 mg Tablet.
  • Maintain a balanced diet rich in whole grains, fruits, and vegetables to support overall health.
  • Avoid high-fat meals that may exacerbate gastrointestinal side effects associated with Istamet XR 500 mg Tablet.
  • Carry a source of fast-acting sugar for emergencies in case of hypoglycemia episodes.
  • Regularly check your feet for any sores or infections as part of diabetes management while on Istamet XR 500 mg Tablet.

Side Effects

  • Common side effects of Istamet XR 500 mg Tablet include stomach upset, nausea, and diarrhea.
  • Mild headaches may occur during treatment with Istamet XR 500 mg Tablet.
  • Cold-like symptoms such as a runny nose or sore throat can also be experienced.
  • Uncommon side effects may include skin rash, joint pain, or changes in taste.
  • Serious side effects requiring immediate medical attention include lactic acidosis, characterized by severe fatigue or difficulty breathing.
  • Pancreatitis symptoms such as severe abdominal pain radiating to the back should be reported promptly.
  • Monitor for any signs of severe allergic reactions like swelling of the face or throat while using Istamet XR 500 mg Tablet.

Precautions and Warnings

  • Istamet XR 500 mg Tablet should not be used in individuals with severe kidney impairment due to the risk of lactic acidosis.
  • Caution is advised for patients with liver disease; regular monitoring may be necessary.
  • Avoid excessive alcohol consumption while taking Istamet XR 500 mg Tablet as it may increase lactic acidosis risk.
  • Pregnant women should only use this medication if clearly indicated; insulin is often preferred during pregnancy.
  • Breastfeeding while using Istamet XR 500 mg Tablet is generally not recommended due to limited data on safety.
  • Your ability to drive may be impaired if blood sugar levels are too low or too high; exercise caution.
1. What is Istamet XR 500 mg Tablet used for?
Istamet XR 500 mg Tablet is prescribed to improve blood sugar control in adults with type 2 diabetes when diet and exercise alone are insufficient.
2. How does Istamet XR 500 mg Tablet work?
This medication enhances insulin effectiveness and reduces excess glucose production by the liver, leading to better blood sugar management.
3. When should I take Istamet XR 500 mg Tablet?
It is typically taken with meals to minimize stomach upset; follow your doctor's instructions regarding timing.
4. How long does it take for Istamet XR 500 mg Tablet to lower blood sugar?
Initial improvements may be seen within days, but full benefits usually take several weeks of consistent use.
5. Can I drink alcohol while taking Istamet XR 500 mg Tablet?
It's advisable to limit alcohol intake as it can increase the risk of side effects associated with this medication.
6. Is Istamet XR 500 mg Tablet safe for long-term use?
Yes, it is often used long-term under medical supervision; regular monitoring of health parameters is essential.
7. What should I do if I miss a dose of Istamet XR 500 mg Tablet?
Take it as soon as you remember unless it's close to your next dose; do not double up on doses.

Directions for Use

Use only as prescribed by your physician.

Storage and Disposal

Please refer to the product label for storage information.
SKU 291077
Country of Manufacture India
Manufacturer Address Sun Pharmaceutical Industries Ltd
Return/Buy Back policy Non-returnable
Prescription Required Yes
Storage Please refer to the product label for storage information.
Seller Kogland Commerce Pvt Ltd (TN)

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