Istamet G IR 50/500/2 mg Tablet - Strip of 10

Prescription Required

Compositions : Glimepiride 2mg + Metformin Hydrochloride 500mg + Sitagliptin 50mg

₹125.30 (Incl. GST)

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Delivery within 2 to 7 Working Days

Manufacture/Marketer: Sun Pharmaceutical Industries Ltd

Istamet G IR 50/500/2 mg Tablet is a pharmaceutical formulation designed to manage blood sugar levels in individuals diagnosed with type 2 diabetes mellitus. This medication combines three active ingredients: Glimepiride, Metformin, and Sitagliptin, each contributing to its therapeutic efficacy. Glimepiride is a sulfonylurea that stimulates insulin secretion from the pancreas, thereby lowering blood glucose levels. Metformin, a biguanide, enhances insulin sensitivity and decreases hepatic glucose production, making it a cornerstone in diabetes management. Sitagliptin, a DPP-4 inhibitor, works by increasing incretin levels, which helps regulate insulin secretion in response to meals. The synergistic action of these components makes Istamet G IR 50/500/2 mg Tablet an effective option for patients struggling to achieve glycemic control through diet and exercise alone. It is typically prescribed when monotherapy or dual therapy has not been sufficient in managing blood glucose levels. The tablet is intended for oral administration and is usually taken with meals to minimize gastrointestinal side effects. By addressing multiple pathways involved in glucose metabolism, Istamet G IR 50/500/2 mg Tablet provides a comprehensive approach to diabetes management, aiming to improve overall glycemic control and reduce the risk of diabetes-related complications.

Uses & Benefits

  • Helps lower blood sugar levels in adults with type 2 diabetes.
  • Combines three mechanisms of action for enhanced glycemic control.
  • Reduces the risk of diabetes-related complications.
  • Improves insulin sensitivity and secretion.
  • Can be used as part of a comprehensive diabetes management plan including diet and exercise.
  • May help in weight management compared to other diabetes medications.
  • Convenient once-daily dosing improves adherence to treatment.
How Istamet G IR 50/500/2 mg Tablet works

  • Glimepiride stimulates the pancreas to release more insulin.
  • Metformin decreases glucose production in the liver and increases insulin sensitivity in muscle tissues.
  • Sitagliptin inhibits the DPP-4 enzyme, leading to increased levels of incretin hormones.
  • Incretins enhance insulin secretion in response to meals and decrease glucagon release.
  • The combination of these actions leads to improved blood sugar control throughout the day.
How to use Istamet G IR 50/500/2 mg Tablet

  • Take Istamet G IR 50/500/2 mg Tablet orally with meals to reduce gastrointestinal side effects.
  • The typical starting dose is one tablet daily, as prescribed by your healthcare provider.
  • Dosage may be adjusted based on blood glucose monitoring results.
  • Do not exceed the prescribed dose without consulting your doctor.
  • Maintain regular follow-up appointments for monitoring blood sugar levels.
  • If you miss a dose, take it as soon as you remember unless it's almost time for your next dose; do not double up.
Lifestyle Advice

  • Adopt a balanced diet rich in whole grains, vegetables, lean proteins, and healthy fats.
  • Engage in regular physical activity, aiming for at least 150 minutes of moderate exercise weekly.
  • Monitor blood sugar levels regularly to understand how food and activity affect your diabetes.
  • Avoid excessive alcohol consumption as it can affect blood sugar levels.
  • Stay hydrated by drinking plenty of water throughout the day.
  • Manage stress through relaxation techniques such as yoga or meditation.

Side Effects

  • Common side effects include nausea, vomiting, diarrhea, abdominal pain, and headache.
  • Serious side effects may include hypoglycemia (low blood sugar), lactic acidosis, and allergic reactions.
  • If you experience symptoms of hypoglycemia such as sweating, shaking, or confusion, seek medical attention immediately.
  • Contact your healthcare provider if you notice unusual fatigue or muscle pain, which may indicate lactic acidosis.
  • Always report any severe allergic reactions like rash, itching, or difficulty breathing to your doctor promptly.

Precautions and Warnings

  • Avoid using Istamet G IR 50/500/2 mg Tablet if you have a known allergy to any of its components.
  • Use with caution in patients with kidney or liver impairment; dosage adjustments may be necessary.
  • Alcohol consumption should be limited as it can increase the risk of hypoglycemia and lactic acidosis.
  • Consult your doctor before using this medication if you are pregnant or breastfeeding.
  • Monitor blood sugar levels regularly while on this medication to avoid complications.
  • If you experience symptoms such as severe abdominal pain or difficulty breathing, seek immediate medical attention.
1. What should I do if I miss a dose of Istamet G IR 50/500/2 mg Tablet?
If you miss a dose, take it as soon as you remember unless it's close to your next scheduled dose. Do not double up on doses.

2. Can I take Istamet G IR 50/500/2 mg Tablet if I am pregnant?
Consult your healthcare provider before taking Istamet G IR 50/500/2 mg Tablet during pregnancy, as it may not be safe.

3. Are there any food interactions with Istamet G IR 50/500/2 mg Tablet?
It's recommended to take Istamet G IR 50/500/2 mg Tablet with meals to minimize gastrointestinal side effects.

4. What are the common side effects of Istamet G IR 50/500/2 mg Tablet?
Common side effects may include nausea, headache, dizziness, and gastrointestinal discomfort.

5. Who should avoid using Istamet G IR 50/500/2 mg Tablet?
Individuals with severe kidney impairment or those allergic to any component of the tablet should avoid its use.

6. How should I store Istamet G IR 50/500/2 mg Tablet?
Store Istamet G IR 50/500/2 mg Tablet at room temperature away from moisture and heat.

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SKU 291075
Country of Manufacture India
Manufacturer Address Sun Pharmaceutical Industries Ltd
Return/Buy Back policy Non-returnable
Prescription Required Yes
Seller Kogland Commerce Pvt Ltd (TN)

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